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What is AWS Healthlake: Benefits and use cases

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Sarthak Tyagi

Web Developer | AWS Cloud Architect

AWS

Last Updated on August, 03 2025

Discover how AWS Healthlake HIPAA-eligible service uses FHIR, NLP, and ML to unify siloed data, accelerate research, and transform patient care. Explore benefits, use cases, architecture, pricing, and real-world case studies.

Unlocking Healthcare's Future: A Simple Guide to AWS HealthLake

In the world of healthcare, information is everything. But often, this important information—like doctor's notes, lab results, and patient histories—is scattered across many different computer systems. It's like having puzzle pieces in a dozen different boxes, making it hard to see the big picture. This is a huge challenge for doctors, researchers, and hospitals.

This is where AWS HealthLake comes in. It’s a special tool from Amazon Web Services (AWS) built to solve this exact problem. It brings all that scattered health data into one safe, organized place in the cloud, making it easy to understand and use.

What is AWS HealthLake?

AWS HealthLake is a service that securely stores, organizes, and analyzes health information. 1 It’s designed for hospitals, clinics, insurance companies, and researchers. 1 Think of it as a super-smart digital filing cabinet for health data. 

What makes it special is that it’s a HIPAA-eligible service, which means it meets the high standards for privacy and security required for patient information in the United States. It takes all kinds of data—from typed reports to handwritten notes—and turns it into a standard format that computers can easily read and share. 4 This standard is called

FHIR (Fast Healthcare Interoperability Resources), and it's like a common language for health data. 

By putting everything into this one system and one language, AWS HealthLake helps create a complete and organized view of a patient's health journey over time.

How AWS HealthLake Works: A 4-Step Process

AWS HealthLake is a HIPAA-eligible service that enables healthcare providers, health insurance companies, and pharmaceutical companies to store, transform, query, and analyze health data at scale. It uses the Fast Healthcare Interoperability Resources (FHIR) R4 industry standard format to provide a complete view of individual and patient population health data. Here’s a 4-step process that explains how it works:

Gautam IT Services

Gautam IT Services

Step 1: Ingest and Store Data

The first step is to get your health data into AWS HealthLake. You can import data from on-premises systems or other cloud storage services. HealthLake supports various data formats, including HL7v2, CCDA, and flat files, and can ingest data in real-time or in batches. All data is stored in a secure, compliant, and auditable manner in the AWS Cloud. HealthLake uses Amazon S3 for durable and cost-effective storage, ensuring your data is protected and meets regulatory compliance.

Step 2: Transform and Normalize Data

Once the data is ingested, AWS HealthLake transforms it into the FHIR (Fast Healthcare Interoperability Resources) format. This is a standard for exchanging healthcare information electronically. By normalizing the data to the FHIR standard, HealthLake ensures that information from different sources is consistent and can be easily understood and shared. This creates a complete and chronological view of each patient's medical history.

Step 3: Process and Enrich Data

With the data now in a standardized format, AWS HealthLake uses integrated medical natural language processing (NLP) to process and enrich the data. The NLP models are trained to understand and extract meaningful information from unstructured medical text, such as doctor's notes, lab reports, and insurance claims. It can identify medical conditions, medications, procedures, and other important clinical entities. This process transforms raw, unstructured data into structured, queryable data.

Step 4: Analyze and Gain Insights

The final step is to analyze the data and gain insights. You can use standard FHIR APIs to query the data and build applications for patient monitoring, population health analytics, and clinical trial recruitment. AWS HealthLake is also integrated with other AWS services like Amazon QuickSight for data visualization and Amazon SageMaker for building, training, and deploying machine learning models. This allows you to identify trends, make predictions, and ultimately, improve patient care.

Real-World Examples of AWS HealthLake

Many healthcare organizations are already using AWS HealthLake to do amazing things.

Greenway Health: Saving Money and Speeding Up Innovation

Greenway Health, a company that provides EHR software, was struggling with an old system that was slow and expensive. By moving to AWS HealthLake, they were able to load billions of patient records very quickly and without errors. This switch is expected to save them nearly $1.9 million by 2025 and has allowed their developers to build new tools for doctors much faster.

Children's Hospital of Philadelphia (CHOP): Accelerating Cancer Research

Researchers at CHOP are fighting to find cures for childhood brain tumors. They use AWS HealthLake to bring together data from thousands of patients across more than 35 different studies.  This gives them a single, reliable source of information, making it much easier to find patterns and identify groups of patients for clinical trials, speeding up the pace of discovery. 

Cortica: Improving Care for Children with Autism

Cortica provides care for children with autism and other developmental conditions. They used AWS HealthLake to build a central platform for all their patient information in just a few weeks. This gives their doctors a deeper understanding of each child's progress and helps them track treatment goals in a way that wasn't possible before. 15

Use Cases of AWS HealthLake

The power of organized health data opens up many possibilities. Here are some key ways AWS HealthLake is being used:

  1. Population Health Management: By looking at data from thousands of people, health officials can spot trends, track diseases, and find groups who need extra help or support.
  2. Clinical Research: Researchers can quickly find patients who are eligible for clinical trials, which can dramatically speed up the development of new medicines and treatments.
  3. Health Tech Innovation: New technology companies can build apps for things like telehealth or patient monitoring on top of HealthLake, allowing them to create new products faster without having to build a complex data system from scratch.
  4. Insurance Operations: Insurance companies can get a complete view of their members to better manage care, identify risks, and streamline processes like quality reporting.

Pricing

AWS HealthLake uses a "pay-as-you-go" model, which means there are no big upfront costs, and you only pay for what you use. 17 The pricing is broken down into a few main parts.

Service ComponentHow It's PricedSimple Explanation
Data Store$0.27 per hourThis is the cost to keep your data "filing cabinet" running. It includes importing data and the first 10 GB of storage. 
Data Storage$0.37 per GB per month (for storage over 10 GB) If you have a lot of data (more than 10 GB), you pay a small amount for the extra space.
Queries$0.048 per 10,000 queries (after 3,500 free queries per hour)You get a lot of searches for free. You only pay if you are searching the data very frequently.
Integrated NLP$0.0010 per 100 charactersThis is the cost for the smart AI that reads and understands your text-based data.
Data Export$0.19 per GB This is the cost to move your organized data out of HealthLake to use with other tools like for analytics or machine learning.

Note: Prices are for the HealthLake Advanced tier and are based on the US East (N. Virginia) region. Prices can vary and are subject to change. You can get a custom estimate using the AWS Pricing Calculator.

Strategic Considerations for Adoption

Moving to a new system like AWS HealthLake is a big step. Here are some simple but important things to think about before you start: 

  1. What is our main goal? Are you trying to improve research, make reporting easier, or build new AI tools? Knowing your goal helps you focus. 
  2. Where is our data now? Make a list of all your current systems and the types of data you have. Is the data clean and organized, or is it messy? 
  3. Who will be in charge? After the data is moved, someone needs to manage it to make sure it stays high-quality and secure. 
  4. Do we need help? Migrating health data can be tricky because of its complexity and privacy rules. You might need to work with experts who have experience with both AWS and healthcare. 

Benefits of AWS HealthLake

Adopting AWS HealthLake offers many powerful advantages for healthcare organizations.

  1. See the Full Picture: Doctors get a complete, 360-degree view of a patient's health history, leading to better, safer care. 
  2. Save Time and Money: It automates many of the difficult tasks of data management, which saves time for IT teams and reduces costs. 
  3. Top-Notch Security: As a HIPAA-eligible service, it provides a secure environment designed to protect sensitive patient data. 
  4. Unlock New Insights: By organizing unstructured data, it makes it possible to use advanced tools like AI and machine learning to find trends and make predictions. 
  5. Be Ready for the Future: It uses the industry-standard FHIR format, which makes it easier to connect with other modern health systems and comply with regulations. 
  6. Grow Without Worry: It's built on the AWS cloud, so it can easily handle more and more data as your organization grows. 

Challenges While Adopting AWS HealthLake

While HealthLake is powerful, the journey to adopt it has some challenges to be aware of.

  1. Data Cleanup: Most organizations have data that is messy, incomplete, or inconsistent. This data needs to be cleaned up before it can be moved into HealthLake, which can take time and effort.
  2. Learning New Standards: The FHIR standard is key to HealthLake's power, but it can have a learning curve for teams that are new to it. 
  3. Connecting to Old Systems: Many hospitals rely on older, legacy systems that can be difficult to connect to modern cloud services. This often requires custom work or help from specialized partners.
  4. Managing the System: HealthLake is a "managed service," but it's not completely hands-off. You still need people to manage data flows, control who has access, and keep things running smoothly.
  5. Cost Management: While the pay-as-you-go model is flexible, costs can become unpredictable if you are performing a very large number of queries or analyzing huge amounts of text with NLP. It's important to monitor usage.

Alternatives to AWS HealthLake

AWS isn't the only player in this space. The other major cloud providers offer similar services for healthcare data.

Microsoft Azure Health Data Services

This is Microsoft's offering. It's a strong choice for organizations that already use a lot of Microsoft products, like Power BI for analytics. 19 It also provides a collection of tools for managing protected health information (PHI) and is built on open standards like FHIR.

Google Cloud Healthcare API

Google's platform is known for its powerful AI, machine learning, and large-scale data analytics tools like BigQuery. 19 It's a great option for organizations that want to do very advanced analysis and build predictive models with their health data.

Conclusion

AWS HealthLake is a game-changing tool for the healthcare industry. It directly tackles the huge problem of scattered and messy data by bringing it all together in one secure, organized, and intelligent platform. By turning complex medical information into a simple, standard format, it empowers doctors to provide better care, helps researchers make discoveries faster, and allows hospitals to run more efficiently.

For any healthcare organization looking to step into a data-driven future, AWS HealthLake offers a powerful foundation for innovation and a clearer path toward improving the health of people everywhere.

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